Post-Streptococcal Uveitis: A Narrative Literature Review

Streptococcus spp. are gram-positive bacteria and common human pathogens commensals, causing diseases of various organs in children adults. They etiological factors scarlet fever, pharyngitis, tonsillitis, pneumonia, endocarditis, erysipelas, impetigo, meningitis, necrotising fasciitis, sepsis, among others. The post-streptococcal syndrome is a presumed autoimmune condition that has been associated with rheumatism, reactive arthritis, glomerulonephritis, erythema nodosum. This literature review aimed to describe uveitis clinical practice. onset the immune-mediated complications varied from 7 35 days post-infection. ocular present mainly form blepharoconjunctivitis. There anecdotal case reports episcleritis. Keratitis another possible complication. Preseptal or orbital cellulitis also described. Uveitis much rarer finding, it hypothesized pathogenesis rather than due intraocular bacterial infection. Post-streptococcal described cases both group A B infections. 1 week 36 months after presents mostly as nongranulomatous, bilateral anterior good prognosis affects young people. Nevertheless, all anatomic types inflammation have observed. denominators between varying pictures appear be history streptococcal infection, most frequently an elevated anti-streptolysin O titer, more recent studies-the raised anti-deoxyribonuclease antibodies. Furthermore, there generally therapeutic response corticosteroids. Few required immunomodulation methotrexate, mycophenolate, adalimumab.